Get Back To Normal!
A simple, innovative, earlier treatment option for the world’s #1 source of disability - Back Pain!
Triojection™ From SpinaFX Medical
Minimally-Invasive Image-Guided Ozone Therapy1 .
Ozone generator and measurement console
Syringe with exterior case, filter and dual stopcocks.
- Indicated for patients with “Contained Herniated Discs” causing back pain which has not responded to conservative therapy1,2.
- Triojection combines a self-contained, medical-grade ozone (O3) generator, spectroscopic measurement console, and disposable single-use delivery syringe and sterile case.
- Triojection ensures consistent treatment with accurate, repeatable O3 concentration.
- Our patented, disposable exterior case and syringe adheres to key aseptic principles guaranteeing sterile O3 delivery.
- Built with Ozone- and UV-compatible disposable syringe polymers including filters & stopcocks.
1.Triojection™ is not currently available for promotion or sale in the USA or EU. Triojection was previously awarded CE Mark under MDD and is undertaking re-registration under MDR. Contact SpinaFX for further information regarding anticipated commercial availability in your region.
2. Eligible patients include 71% of those with contained herniated discs and other borderline non-surgical patients for whom there are no effective treatment options.
A Simple, Innovative, Earlier Solution for
Herniated Disc-Related Back Pain.
Back Pain – The #1 cause of disability in the world1 and most expensive health condition treated2.
- An earlier treatment option that reduces the risk and pain that can be associated with surgery.
- Avoids further disc and/or vertebral damage but still allows surgery if needed as the patient ages3.
- 62% faster for physicians and 10 times less costly, averaging 4.3 hours of hospital stay vs 44 hours for surgery3.
- Can eliminate pain with long-lasting effect, reducing the need for opioids and/or steroids.
1.NIH Low Back Pain Fact Sheet https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Low-Back-Pain-Fact-Sheet
2.Dieleman JL, Cao J, Chapin A, et al. US Health Care Spending by Payer and Health Condition, 1996-2016. JAMA. 2020;323(9):863–884. doi:10.1001/jama.2020.0734
3.Murphy K P et al. Intradiscal Oxygen-Ozone Chemo-nucleolysis versus Microdiscectomy for Lumbar Disc Herniation Radiculopathy: A Non-inferiority Randomized Control Trial. Accepted for Publication in ‘Spine’.
How Ozone (O3) works
Ozone (O3) – a dehydrating, oxidizing, naturally occurring species of oxygen (O2) gas that can be injected into the gelatinous disc nucleus.
Nucleus Pulposus Breakdown
Ozone injected into the disc nucleus dehydrates and breaks down proteins* in the nucleus leading to reduction of the bulging disc herniation.
* Glycosaminoglycans (GAGs)-substituted proteoglycans
Murphy 2016, pubmed.ncbi.nlm.nih.gov/27363296/
Lehnert T 2012, pubmed.ncbi.nlm.nih.gov/22999458/
Reduces Inflammation
Ozone reduces the release of inflammatory proteins (cytokines) that lead to inflammation.
Niu 2018, pubmed.ncbi.nlm.nih.gov/29611536/
Murphy 2016, pubmed.ncbi.nlm.nih.gov/27363296/
Fuccio 2008, pubmed.ncbi.nlm.nih.gov/19100257/
Chang 2005 link.springer.com/article/10.1007/s00296-004-0526-1
Lu 2017, pubmed.ncbi.nlm.nih.gov/27744376/
Reduces Infection
Ozone has proven antimicrobial properties. Reduced spine infection reduces potential degenerative (modic) changes in the disc, vertebral bones and reduces pain.
Albert 2013 pubmed.ncbi.nlm.nih.gov/23397187/
Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18-month trial. Gerodontology. 2003 Dec;20(2):106-14. doi: 10.1111/j.1741-2358.2003.00106.x. PMID: 14697022.
Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18-month trial. Gerodontology. 2003 Dec;20(2):106-14. doi: 10.1111/j.1741-2358.2003.00106.x. PMID: 14697022.
Triojection vs discectomy
Shorter Procedure
62%
Shorter Stay
90%
Lower Cost
90%
Patients Are Eligible
70%
Success Rate
71%
TRIOJECTION
17/24 (71%) of Ozone patients
avoided open surgery entirely.
(Surgery can be done after triojection if needed in future)
(Surgery can be done after triojection if needed in future)
DISCECTOMY
2/17 (12%) of surgical patients required repeat surgery
for persistent symptoms.
* Murphy K P et al. Intradiscal Oxygen-Ozone Chemo-nucleolysis versus Microdiscectomy for Lumbar Disc Herniation Radiculopathy: A Non-inferiority Randomized Control Trial. Accepted for Publication in ‘Spine’.