80% success rate and 20% failure rate in 1750 patients followed up to 6 months. Success dropped to 75% and failure increased at 25% in 1400 followed up to 18 months.
Prospective, double blind, RCT; Ozone + ESI vs ESI alone.
75% of patients were able to avoid surgery, and of the patients that avoided surgery, 82% improved at 5 years, and 88% improved at 10 years. 79% of patients had a reduction in herniation volume and the average reduction was 56%.
62.5-85% in terms of leg pain relief.
The likelihood of showing improvement on the modified MacNab
scale was 79.7%.
9 superior, 3 equivalent to control, 3 not assessed.
71% of patients avoided surgery. Non-inferior to microdiscectomy surgery.